(AQA) GCSE Combined Science: Trilogy – Knowness

Welcome to the GCSE Combined Science: Trilogy study guide for the AQA exam board! This study guide is structured to cover all of the topics in the AQA specification, providing you with all of the essential information you need for your GCSE examinations.

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GCSE Combined Science 2 Topics FREE

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Introduction to GCSE Combined Science

Assessment Structure

Biology: 1 Cell Biology

1.1 Cell Structure 6 Topics FREE

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1.1.1 Eukaryotes and Prokaryotes

1.1.2 Animal and Plant Cells

Required Practical Activity 1

1.1.3 Cell Specialisation

1.1.4 Cell Differentiation

1.1.5 Microscopy

1.2 Cell Division 3 Topics

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1.2.1 Chromosomes

1.2.2 Mitosis and the Cell Cycle

1.2.3 Stem Cells

1.3 Transport in Cells 4 Topics

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1.3.1 Diffusion

Required Practical Activity 2

1.3.3 Active Transport

Biology: 2 Organisation

2.1 Principles of Organisation

2.2 Animal Tissues, Organs and Organ Systems 9 Topics

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2.2.1 The Human Digestive System

Required Practical Activity 3

Required Practical Activity 4

2.2.2 The Heart and Blood Vessels

2.2.4 Coronary Heart Disease: A Non-communicable Disease

2.2.5 Health Issues

2.2.6 The Effect of Lifestyle on Some Non-communicable Diseases

2.3 Plant Tissues, Organs and Systems 2 Topics

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2.3.1 Plant Tissues

2.3.2 Plant Organ System

Biology: 3 Infection and Response

3.1 Communicable Diseases 9 Topics

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3.1.1 Communicable (Infectious) Diseases

3.1.2 Viral Diseases

3.1.3 Bacterial Diseases

3.1.4 Fungal Diseases

3.1.5 Protist Diseases

3.1.6 Human Defence Systems

3.1.7 Vaccination

3.1.8 Antibiotics and Painkillers

3.1.9 Discovery and Development of Drugs

Biology: 4 Bioenergetics

4.1 Photosynthesis 4 Topics

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4.1.1 Photosynthetic Reaction

4.1.2 Rate of Photosynthesis

Required Practical Activity 5

4.1.3 Uses of Glucose from Photosynthesis

4.2 Respiration 3 Topics

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4.2.1 Aerobic and Anaerobic Respiration

4.2.2 Response to Exercise

4.2.3 Metabolism

Biology: 5 Homeostasis and Response

5.1 Homeostasis

5.2 The Human Nervous System 1 Topic

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Required Practical Activity 6

5.3 Hormonal Coordination in Humans 6 Topics

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5.3.1 Human Endocrine System

5.3.2 Control of Blood Glucose Concentration

5.3.3 Hormones in Human Reproduction

5.3.4 Contraception

5.3.5 The Use of Hormones to Treat Infertility (HT only)

5.3.6 Feedback Systems (HT only)

Biology: 6 Inheritance, Variation and Evolution

6.1 Reproduction 6 Topics

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6.1.1 Sexual and Asexual Reproduction

6.1.3 DNA and the Genome

6.1.4 Genetic Inheritance

6.1.5 Inherited Disorders

6.1.6 Sex Determination

6.2 Variation and Evolution 4 Topics

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6.2.1 Variation

6.2.2 Evolution

6.2.3 Selective Breeding

6.2.4 Genetic Engineering

6.3 The Development of Understanding of Genetics and Evolution 4 Topics

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6.3.1 Evidence for Evolution

6.3.3 Extinction

6.3.4 Resistant Bacteria

6.4 Classification of Living Organisms

Biology: 7 Ecology

7.1 Adaptations, Interdependence and Competition 4 Topics

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7.1.1 Communities

7.1.2 Abiotic Factors

7.1.3 Biotic Factors

7.1.4 Adaptations

7.2 Organisation of an Ecosystem 3 Topics

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7.2.1 Levels of Organisation

Required Practical Activity 7

7.2.2 How Materials are Cycled

7.3 Biodiversity and the Effect of Human Interaction on Ecosystems 6 Topics

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7.3.1 Biodiversity

7.3.2 Waste Management

7.3.4 Deforestation

7.3.5 Global Warming

7.3.6 Maintaining Biodiversity

Chemistry: 1 Atomic Structure and the Periodic Table

1.1 A Simple Model of the Atom, Symbols, Relative Atomic Mass, Electronic Charge and Isotopes 7 Topics

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1.1.1 Atoms, Elements and Compounds

1.1.3 The Development of the Model of the Atom

1.1.4 Relative Electrical Charges of Subatomic Particles

1.1.5 Size and Mass of Atoms

1.1.6 Relative Atomic Mass

1.1.7 Electronic Structure

1.2 The Periodic Table 6 Topics

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1.2.1 The Periodic Table

1.2.2 Development of the Periodic Table

1.2.3 Metals and Non-Metals

Chemistry: 2 Bonding, Structure, and the Properties of Matter

2.1 Chemical Bonds, Ionic, Covalent and Metallic 5 Topics

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2.1.1 Chemical Bonds

2.1.2 Ionic Bonding

2.1.3 Ionic Compounds

2.1.4 Covalent Bonding

2.1.5 Metallic Bonding

2.2 How Bonding and Structure are Related to the Properties of Substances 8 Topics

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2.2.1 The Three States of Matter

2.2.2 State Symbols

2.2.3 Properties of Ionic Compounds

2.2.4 Properties of Small Molecules

2.2.6 Giant Covalent Structures

2.2.7 Properties of Metals and Alloys

2.2.8 Metals as Conductors

2.3 Structure and Bonding of Carbon 3 Topics

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2.3.3 Graphene and Fullerenes

Chemistry: 3 Quantitative Chemistry

3.1 Chemical Measurements, Conservation of Mass and the Quantitative Interpretation of Chemical Equations 4 Topics

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3.1.1 Conservation of Mass and Balanced Chemical Equations

3.1.2 Relative Formula Mass

3.1.3 Mass Changes When a Reactant or Product Is a Gas

3.1.4 Chemical Measurements

3.2 Use of Amount of Substance in Relation to Masses of Pure Substances 5 Topics

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3.2.1 Moles (HT only)

3.2.2 Amounts of Substances in Equations (HT only)

3.2.3 Using Moles to Balance Equations (HT only)

3.2.4 Limiting Reactants (HT only)

3.2.5 Concentration of Solutions

Chemistry: 4 Chemical Changes

4.1 Reactivity of Metals 4 Topics

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4.1.1 Metal Oxides

4.1.2 The Reactivity Series

4.1.3 Extraction of Metals and Reduction

4.1.4 Oxidation and Reduction in Terms of Electrons (HT only)

4.2 Reactions of Acids 6 Topics

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4.2.1 Reactions of Acids with Metals

4.2.2 Neutralisation of Acids and Salt Production

4.2.3 Soluble Salts

Required Practical Activity 8

4.2.4 The pH Scale and Neutralisation

4.2.5 Strong and Weak Acids (HT only)

4.3 Electrolysis 6 Topics

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4.3.1 The Process of Electrolysis

4.3.2 Electrolysis of Molten Ionic Compounds

4.3.3 Using Electrolysis to Extract Metals

4.3.4 Electrolysis of Aqueous Solutions

Required Practical Activity 9

4.3.5 Representation of Reactions at Electrodes as Half Equations (HT only)

Chemistry: 5 Energy Changes

5.1 Exothermic and Endothermic Reactions 4 Topics

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5.1.1 Energy Transfer During Exothermic and Endothermic Reactions

Required Practical Activity 10

5.1.2 Reaction Profiles

5.1.3 The Energy Change of Reactions (HT only)

Chemistry: 6 The Rate and Extent of Chemical Change

6.1 Rate of Reaction 5 Topics

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6.1.1 Calculating Rates of Reactions

6.1.2 Factors Which Affect the Rates of Chemical Reactions

Required Practical Activity 11

6.1.3 Collision Theory and Activation Energy

6.1.4 Catalysts

6.2 Reversible Reactions and Dynamic Equilibrium 7 Topics

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6.2.1 Reversible Reactions

6.2.2 Energy Changes and Reversible Reactions

6.2.3 Equilibrium

6.2.4 The Effect of Changing Conditions on Equilibrium (HT only)

6.2.5 The Effect of Changing Concentration (HT only)

6.2.6 The Effect of Temperature Changes on Equilibrium (HT only)

6.2.7 The Effect of Pressure Changes on Equilibrium (HT only)

Chemistry: 7 Organic Chemistry

7.1 Carbon Compounds as Fuels and Feedstock 4 Topics

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7.1.1 Crude Oil, Hydrocarbons and Alkanes

7.1.2 Fractional Distillation and Petrochemicals

7.1.3 Properties of Hydrocarbons

7.1.4 Cracking and Alkenes

Chemistry: 8 Chemical Analysis

8.1 Purity, Formulations and Chromatography 4 Topics

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8.1.1 Pure Substances

8.1.2 Formulations

8.1.3 Chromatography

Required Practical Activity 12

8.2 Identification of Common Gases 4 Topics

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8.2.1 Test for Hydrogen

8.2.2 Test for Oxygen

8.2.3 Test for Carbon Dioxide

8.2.4 Test for Chlorine

Chemistry: 9 Chemistry of the Atmosphere

9.1 The Composition and Evolution of the Earth’s Atmosphere 4 Topics

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9.1.1 The Proportions of Different Gases in the Atmosphere

9.1.2 The Earth’s Early Atmosphere

9.1.3 How Oxygen Increased

9.1.4 How Carbon Dioxide Decreased

9.2 Carbon Dioxide and Methane as Greenhouse Gases 4 Topics

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9.2.1 Greenhouse Gases

9.2.2 Human Activities Which Contribute to an Increase in Greenhouse Gases in the Atmosphere

9.2.3 Global Climate Change

9.2.4 The Carbon Footprint and its Reduction

9.3 Common Atmospheric Pollutants and Their Sources 2 Topics

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9.3.1 Atmospheric Pollutants from Fuels

9.3.2 Properties and Effects of Atmospheric Pollutants

Chemistry: 10 Using Resources

10.1 Using the Earth’s Resources and Obtaining Potable Water 5 Topics

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10.1.1 Using the Earth’s Resources and Sustainable Development

10.1.2 Potable Water

Required Practical Activity 13

10.1.3 Waste Water Treatment

10.1.4 Alternative Methods of Extracting Metals (HT only)

10.2 Life Cycle Assessment and Recycling 2 Topics

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10.2.1 Life Cycle Assessment

10.2.2 Ways of Reducing the Use of Resources

Physics: 1 Energy

1.1 Energy Changes in a System, and the Ways Energy is Stored Before and After Such Changes 5 Topics

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1.1.1 Energy Stores and Systems

1.1.2 Changes in Energy

1.1.3 Energy Changes in Systems

Required Practical Activity 14

1.2 Conservation and Dissipation of Energy 2 Topics

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1.2.1 Energy Transfers in a System

1.2.2 Efficiency

1.3 National and Global Energy Resources

Physics: 2 Electricity

2.1 Current, Potential Difference and Resistance 6 Topics

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2.1.1 Standard Circuit Diagram Symbols

2.1.2 Electrical Charge and Current

2.1.3 Current, Resistance and Potential Difference

Required Practical Activity 15

2.1.4 Resistors

Required Practical Activity 16

2.2 Series and Parallel Circuits

2.3 Domestic Uses and Safety 2 Topics

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2.3.1 Direct and Alternating Potential Difference

2.3.2 Mains Electricity

2.4 Energy Transfers 3 Topics

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2.4.2 Energy Transfers in Everyday Appliances

2.4.3 The National Grid

Physics: 3 Particle Model of Matter

3.1 Changes of State and the Particle Model 3 Topics

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3.1.1 Density of Materials

Required Practical Activity 17

3.1.2 Changes of State

3.2 Internal Energy and Energy Transfers 3 Topics

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3.2.1 Internal Energy

3.2.2 Temperature Changes in a System and Specific Heat Capacity

3.2.3 Changes of State and Specific Latent Heat

3.3 Particle Model and Pressure 1 Topic

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3.3.1 Particle Motion in Gases

Physics: 4 Atomic Structure

4.1 Atoms and Isotopes 3 Topics

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4.1.1 The Structure of an Atom

4.1.2 Mass Number, Atomic Number and Isotopes

4.1.3 The Development of the Model of the Atom

4.2 Atoms and Nuclear Radiation 4 Topics

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4.2.1 Radioactive Decay and Nuclear Radiation

4.2.2 Nuclear Equations

4.2.3 Half-Lives and the Random Nature of Radioactive Decay

4.2.4 Radioactive Contamination

Physics: 5 Forces

5.1 Forces and Their Interactions 4 Topics

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5.1.1 Scalar and Vector Quantities

5.1.2 Contact and Non-Contact Forces

5.1.4 Resultant Forces

5.2 Work Done and Energy Transfer

5.3 Forces and Elasticity 1 Topic

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Required Practical Activity 18

5.4 Forces and Motion 13 Topics

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5.4.1.1 Distance and Displacement

5.4.1.3 Velocity

5.4.1.4 The Distance–Time Relationship

5.4.1.5 Acceleration

5.4.2.1 Newton’s First Law

5.4.2.2 Newton’s Second Law

Required Practical Activity 19

5.4.2.3 Newton’s Third Law

5.4.3.1 Stopping Distance

5.4.3.2 Reaction Time

5.4.3.3 Factors Affecting Braking Distance 1

5.4.3.4 Factors Affecting Braking Distance 2

5.5 Momentum (HT only) 2 Topics

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5.5.1 Momentum Is a Property of Moving Objects

5.5.2 Conservation of Momentum

Physics: 6 Waves

6.1 Waves in Air, Fluids and Solids 3 Topics

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6.1.1 Transverse and Longitudinal Waves

6.1.2 Properties of Waves

Required Practical Activity 20

6.2 Electromagnetic Waves 5 Topics

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6.2.1 Types of Electromagnetic Waves

6.2.2 Properties of Electromagnetic Waves 1

Required Practical Activity 21

6.2.3 Properties of Electromagnetic Waves 2

6.2.4 Uses and Applications of Electromagnetic Waves

Physics: 7 Magnetism and Electromagnetism

7.1 Permanent and Induced Magnetism, Magnetic Forces and Fields 2 Topics

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7.1.1 Poles of a Magnet

7.1.2 Magnetic Fields

7.2 The Motor Effect 3 Topics

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7.2.1 Electromagnetism

7.2.2 Fleming’s Left-Hand Rule (HT only)

7.2.3 Electric Motors (HT only)

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